Thoughts on Healthcare Markets & Technology
Thoughts on Healthcare Markets & Technology Podcast
Claude Fable 5 Quietly Routes Biology & Chemistry Prompts to an Older Model & What That Safety Lockdown Means for the Cost, Access & Competitive Map of AI Drug Discovery for Pharma, Biotech & Venture
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Claude Fable 5 Quietly Routes Biology & Chemistry Prompts to an Older Model & What That Safety Lockdown Means for the Cost, Access & Competitive Map of AI Drug Discovery for Pharma, Biotech & Venture

Anthropic shipped its most capable public AI model ever, and on day one someone typed ‘mitochondria is the powerhouse of the cell’ and got a safety notice instead of an answer. Here is what is actually going on.

Claude Fable 5 uses topic-level classifiers that quietly route biology, chemistry, and cybersecurity prompts down to the older Opus 4.8. You pay…

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