Sinclair Says Age Reversal Is Already In Humans: What Is Actually Being Dosed, Why The Endpoint Is Vision Instead Of Aging, And What The FDA Would Need To Approve An Actual Geroprotector

A Harvard geneticist told a podcast that human age reversal is ‘in people right now.’ Nearly a million engagements. Almost nobody asked: what molecule, what patients, what endpoint, and what does the regulator actually see?

The most plausible referent is a gene therapy using three Yamanaka reprogramming factors, delivered to retinal ganglion cells, in pa…